Advanced Features:
Exclusive NeoLife Mitogenic Phyto-lipid & Sterol Blend. Sourced from whole grain lipids and sterols known to support optimal mitochondrial structure and function.*

• Provides the four tocotrienols derived from rice known to protect mitochondrial lipid membranes from oxidative attacks.
• Plus, the four most powerful phytosterols; Beta-sitosterol, Campesterol, Stigmasterol and Brassicasterol from soy involved in mitochondrial function.

L-cysteine, the “rate-limiting” amino acid needed for cellular biosynthesis of the mitochondrial protector glutathione. L-cysteine is known to support mitochondrial function and strengthen inner-cellular protective systems.*

NeoLife Proprietary Polyphenol Blend delivers natural, whole-food sourced polyphenols, plus resveratrol from red grapes to provide extra antioxidant protection and to promote mitochondrial protection.*

How it Works

CoQ10 & Mitochondrial Energy Production

Mitochondria
Mitochondria are the powerhouses of your cells. They produce energy by importing food molecules into their membranes and converting them into ATP— the fuel of cellular energy.

Electron Transport
ATP is created within the mitochondrial inner membrane by an “electron transport chain” that passes electrons along in a 3-step process. Steps 1 and 2 require Coenzyme Q-10. If insuficient amounts are not present, energy production is compromised.

CoQ10 & Cholesterol-Lowering Statin Drugs

NeoLife CoQ10 helps restore Coenzyme Q-10 depleted by statin drugs

Effects of Statin Drugs

The unintended consequence of cholesterol-lowering statin drugs (HMG-CoA)—when they block cholesterol synthesis, they also block natural CoQ10 production.

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Tré provides nutrients that support the body’s natural ability to fight the evil twins of aging and disease: inflammation and oxidation.

• Heart Health • Brain Health • Memory • Immunity • Eye Health • Urinary Tract Health

• POMEGRANATE Mental Agility Heart Health polyphenols (standardized to 35% punicalagin)

• ACAI BERRY Antioxidant Protection polyphenols

• GREEN TEA Heart Health Prostate & Breast Health Brain Health standardized to 94% EGCG standardized to 50% total polyphenols

• BLUEBERRY, BLACK CURRANT, ELDERBERRY, BILBERRY, CRANBERRY, WHITE GRAPE polyphenols

• RESVERATROL A nutrient found in red wine, studied for its cardiovascular and genetic protection properties and potential for extending lifespan.

• ALPHA-LIPOIC ACID A powerful, water- and fat-soluble antioxidant that regenerates vitamins C and E and reduces oxidative stress.

• Proprietary Adaptogen Blend of three herbs, studied for their ability to promote mental alertness and overall well-being.

20 TIMES the punicalagins of FRESH POMEGRANATE JUICE!

5-10 TIMES the resveratrol of FINE RED WINE!

7 TIMES the antioxidant power of RIPE RED TOMATOES!

6 TIMES the alpha-lipoic acid of FRESH SPINACH!

Q. Why aren’t the minerals in Formula IV or Formula IV Plus chelated? A. Time tested and proven to be effective and highly bioavailable, Formula IV and Formula IV Plus were developed as multi-factor whole food supplements, with Tre-en-en Grain Concentrates, to support optimal cellular nutrition. These GNLD exclusives have remained unchanged. Chelation mineral technology came after Formula IV’s introduction, however since both Formula IV and Formula IV Plus have a long history of effectiveness in supporting optimal health through cellular nutrition, we have no need or desire to change them.

Q. Is there any gamma linolenic acid in Formula IV or Formula IV Plus? A. Formula IV and Formula IV Plus contain linoleic acid which can be converted to gamma-linolenic acid by the body during metabolism. GNLD does not add gamma-linolenic acid to any of our products, including Formula IV and Formula IV Plus. The body will naturally produce gamma-linolenic acid from linoleic acid, an important component of Formula IV and Formula IV Plus.

Q. What makes Formula IV green? A. The green color in Formula IV is derived from the natural vegetable pigment, chlorophyll.

Q. What information do we have on the initial studies done on Formula IV? Was it a government grant study? A. The research that eventually led to the development of Formula IV began in 1946 at a hospital in Southern California. The focus of the research was on the relationship of endocrine function to reports of chronic fatigue. The results of many studies led researchers to the role of lipids in cell function; and that in turn led to the development of Tre-en-en Concentrates. Formula IV was developed as a multi-factor nutritional supplement, designed to work with the lipids and sterols provided by Tre-en-en. Now the cornerstone of our “Energy Program,” Formula IV (and now also Formula IV Plus) have been credited with giving literally thousands of consumers more energy, vitality, and a general feeling of health and wellness!

Q. I read somewhere that it is not good to take iron in a multi-supplement formula. If this is true, then why is iron in Formula IV? A. We’re not sure why anyone would have stated that iron should not be part of a multivitamin supplement. Iron-deficient diets are still widespread in our population and anemia remains a common health concern. For this reason, Formula IV was formulated to contain a sufficient amount of iron to assure that an adequate and healthy amount of this nutrient is supplied through supplementation. Additionally, Formula IV has been specifically formulated to maximize digestion and absorption of iron. If you are concerned about iron intake and would like an iron-free option, consider Formula IV Plus for your supplementation needs.

Q. What are the sources for all the ingredients in Formula IV and Formula IV Plus? A. Formula IV and Formula IV Plus are not just vitamin and mineral supplements; they are multi-factor food supplements, chock-full of whole food ingredients. Besides containing many of the important vitamins and minerals missing from our diets, they also contain our exclusive Tre-en-en Grain Concentrates. Tre-en-en is the largest component of Formula IV and Formula IV Plus, and the sources are listed on the label, as are many of the other sources of the nutrients used in these products. For example, fish liver oil, the source of vitamin A and vitamin D, is on the Formula IV label. Our approach to product formulation is to always look first to nature for 100% natural, whole food ingredients from the human food chain. Because some natural ingredients are weak, unstable, or unavailable, for some products we next look to natural concentrates or isolates to achieve our formulation goals. Lastly, if the two previous steps don’t deliver the effect we need, then we will select additional pure pharmaceutical-grade ingredients from a list of safe, low-allergy components. These are components which been shown by research to function effectively, providing superior bioavailabilty and overall nutritional excellence. This approach allows us to keep consistent with both nature’s blueprint and the latest scientific nutritional research. It is this approach to excellence that has contributed to GNLD’s distinction and success in the nutrition industry.

Q. Would the yeast in Formula IV and Formula IV Plus affect people with yeast allergies? A. GNLD uses the unique whole-food source of yeast known as Saccharomyces cerevisiae, in Formula IV and Formula IV Plus. This special strain of yeast is “biologically bound” and highly concentrated in B-vitamins and other natural nutritional cofactors. This biologically bound yeast is grown specifically for nutritional application, and through a special process of growing, harvesting, and drying, a naturally high-potency B-vitamin source material is obtained. This is not a living yeast but rather (like the other food-based components in our nutritional products) it is an organic nutrient source that has been harvested and dried. And, as you may be aware, yeast has a long history of safe use, and has been used for decades by people as a source of supplemental nutrition.

Q. What are Tre-en-en Grain Concentrates? A. At the foundation of Formula IV and Formula IV Plus is Tre-en-en Grain Concentrates. This unique and exclusive whole-food blend of extracts from wheat, rice, and soy “feeds your cells” with important phytonutrients. Developed and introduced by GNLD in 1958, Tre-en-en Grain Concentrates is the original phytonutrient supplement. It provides phyto-lipids, including omega-6 and omega-3 fatty acids essential for optimum health and cellular function, plus the plant sterols beta-sitosterol, gamma-oryzanol, stimasterol and campesterol. Besides optimizing cellular nutrition, plant sterols may have other beneficial effects as well. These include reducing cholesterol levels, lowering the risk of atheroscelerosis and inhibiting tumors. Octacosanol, which is a closely related component, is also included to aid in critical biological functions.